The antimutagenic effect of pine needle on frequency of micronucleated polychromatic erythrocytes ( MNPCEs) in mouse bone marrow induced by cyclophosphamide ( C.P.) was studied. 采用腹注和灌喂两种给药方式,研究了松针提取液对环磷酰胺诱发小鼠骨髓细胞微核形成率的影响,以观察松针提取液的抗突变效应以及给药途径对抗突变效应的影响。